Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development

Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development

Summary: Epigenetic regulation of heart development remains incompletely understood. Here we show that LSD1, a histone demethylase, plays a crucial role in regulating cardiomyocyte proliferation during heart development. Cardiomyocyte-specific deletion of Lsd1 in mice inhibited cardiomyocyte prolife...

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Bibliographic Details
Main Authors: Huahua Liu, Rui Zhou, Shanshan Li, Jinling Dong, Yuan Fang, Yuru Luo, Hongyu Su, Baochang Lai, Lingli Liang, Donghong Zhang, Yanmin Zhang, John Y-J. Shyy, Bin Zhou, Zuyi Yuan, Yidong Wang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:iScience
Subjects:
Natural sciences
Biological sciences
Developmental biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223027992

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223027992

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