Exploiting CRISPR-Cas to manipulate Enterococcus faecalis populations
CRISPR-Cas provides a barrier to horizontal gene transfer in prokaryotes. It was previously observed that functional CRISPR-Cas systems are absent from multidrug-resistant (MDR) Enterococcus faecalis, which only possess an orphan CRISPR locus, termed CRISPR2, lacking cas genes. Here, we investigate...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/26664 |