Metabolic regulation of neuronal plasticity by the energy sensor AMPK.

Long Term Potentiation (LTP) is a leading candidate mechanism for learning and memory and is also thought to play a role in the progression of seizures to intractable epilepsy. Maintenance of LTP requires RNA transcription, protein translation and signaling through the mammalian Target of Rapamycin...

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Bibliographic Details
Main Authors: Wyatt B Potter, Kenneth J O'Riordan, David Barnett, Susan M K Osting, Matthew Wagoner, Corinna Burger, Avtar Roopra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2813866?pdf=render