Complement proteins and complement regulatory proteins are associated with age-related macular degeneration stage and treatment response

Complement proteins and complement regulatory proteins are associated with age-related macular degeneration stage and treatment response

Abstract Background Dysregulation of the complement system is involved in development of age-related macular degeneration (AMD). The complement cascade is regulated by membrane bound complement regulatory proteins (Cregs) on mononuclear leukocytes among others. This study aims to investigate systemi...

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Bibliographic Details
Main Authors: Alexander Kai Thomsen, Maria Abildgaard Steffensen, Jenni Martinez Villarruel Hinnerskov, Amalie Thomsen Nielsen, Henrik Vorum, Bent Honoré, Mogens Holst Nissen, Torben Lykke Sørensen
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Neuroinflammation
Subjects:
Neovascular age-related macular degeneration
Intermediate age-related macular degeneration
Complement
Complement regulatory proteins
T cells
Monocytes
Online Access:https://doi.org/10.1186/s12974-024-03273-7

Internet

https://doi.org/10.1186/s12974-024-03273-7

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