Cutaneous and Developmental Effects of <i>CARD14</i> Overexpression in Zebrafish

Background: Gain-of-function mutations in <i>CARD14</i> have recently been shown to be involved in the pathogenesis of psoriasis and pityriasis rubra pilaris (PRP). Those mutations were found to activate the NF-kB signaling pathway. Objective: Zebrafish is often used to model human disea...

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Bibliographic Details
Main Authors: Avital Baniel, Limor Ziv, Zohar Ben-Moshe, Ofer Sarig, Janan Mohamad, Alon Peled, Gideon Rechavi, Yoav Gothilf, Eli Sprecher
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/12/3192