Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M β-lactamase
Structural analysis, antibiotic selection, and deep sequencing of CTX-M-14 mutants identify residues required for β-lactamase activity.
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04422-z |