In vitro inhibitory effects of cepharanthine on human liver cytochrome P450 enzymes

Context Cepharanthine (CEP) extracted from the roots of Stephania cepharantha Hayata (Menispermaceae), has a range of therapeutic potential in clinical conditions. Whether it affects the activity of human liver cytochrome P450 (CYP) enzymes remains unclear. Materials and methods The effects of CEP (...

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Bibliographic Details
Main Authors: Xunge Zhang, Ping Feng, Xinfu Gao, Bin Wang, Chunxia Gou, Ruimin Bian
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Pharmaceutical Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/13880209.2020.1741650