Activation of Peripheral Blood Mononuclear Cells and Leptin Secretion: New Potential Role of Interleukin-2 and High Mobility Group Box (HMGB)1

Activation of Peripheral Blood Mononuclear Cells and Leptin Secretion: New Potential Role of Interleukin-2 and High Mobility Group Box (HMGB)1

Activation of innate immunity and low-grade inflammation contributes to hyperglycemia and an onset of Type 2 Diabetes Mellitus (T2DM). Interleukin-2 (IL-2), leptin, High Mobility Group Box-1 (HMGB-1), and increased glucose concentrations are mediators of these processes also by modulating peripheral...

Full description

Bibliographic Details
Main Authors: Andrea Coppola, Barbara Capuani, Francesca Pacifici, Donatella Pastore, Roberto Arriga, Alfonso Bellia, Aikaterini Andreadi, Nicola Di Daniele, Renato Lauro, David Della-Morte, Giuseppe Sconocchia, Davide Lauro
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
type 2 diabetes mellitus
toll-like receptors system
HMGB1
leptin
Online Access:https://www.mdpi.com/1422-0067/22/15/7988

Internet

https://www.mdpi.com/1422-0067/22/15/7988

Similar Items