Hyperglycemia disturbs trophoblast functions and subsequently leads to failure of uterine spiral artery remodeling

Uterine spiral artery remodeling is necessary for fetal growth and development as well as pregnancy outcomes. During remodeling, trophoblasts invade the arteries, replace the endothelium and disrupt the vascular smooth muscle, and are strictly regulated by the local microenvironment. Elevated glucos...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Yueyue Zhu, Xiaorui Liu, Yichi Xu, Yi Lin
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Frontiers Media S.A. 2023-04-01
Цуврал:Frontiers in Endocrinology
Нөхцлүүд:
Онлайн хандалт:https://www.frontiersin.org/articles/10.3389/fendo.2023.1060253/full