A soft coral-derived compound, 11-epi-sinulariolide acetate suppresses inflammatory response and bone destruction in adjuvant-induced arthritis.

A soft coral-derived compound, 11-epi-sinulariolide acetate suppresses inflammatory response and bone destruction in adjuvant-induced arthritis.

In recent years, a significant number of metabolites with potent anti-inflammatory properties have been discovered from marine organisms, and several of these compounds are now under clinical trials. In the present study, we isolated 11-epi-sinulariolide acetate (Ya-s11), a cembrane-type compound wi...

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Bibliographic Details
Main Authors: Yen-You Lin, Yen-Hsuan Jean, Hsin-Pai Lee, Wu-Fu Chen, Yu-Min Sun, Jui-Hsin Su, Yi Lu, Shi-Ying Huang, Han-Chun Hung, Ping-Jyun Sung, Jyh-Horng Sheu, Zhi-Hong Wen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3652811?pdf=render

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http://europepmc.org/articles/PMC3652811?pdf=render

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