Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation
The objective of the current study was to encapsulate flaxseed oil extracted from finely grounded flaxseed powder and determined for its fatty acids content by GC/FID. Ionotropic gelation method was used to form beads containing 40% flaxseed oil with vitamin E being used as an antioxidant agent. The...
Main Authors: | , |
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Format: | Article |
Language: | English |
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Universidade de São Paulo
2019-12-01
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Series: | Brazilian Journal of Pharmaceutical Sciences |
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100578&tlng=en |
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author | Zam Wissam Housheh Samer |
author_facet | Zam Wissam Housheh Samer |
author_sort | Zam Wissam |
collection | DOAJ |
description | The objective of the current study was to encapsulate flaxseed oil extracted from finely grounded flaxseed powder and determined for its fatty acids content by GC/FID. Ionotropic gelation method was used to form beads containing 40% flaxseed oil with vitamin E being used as an antioxidant agent. The study employed calcium chloride solution as crosslinking agent with a combination of sodium alginate and salep. The effect of polymer concentrations and calcium chloride concentration on the morphology, entrapment efficiency and oil release was studied. The encapsulation efficiency reached 93.46 ± 0.064% using 0.6% of salep and 2% sodium alginate with 0.3M calcium chloride gelling solution. In SGF medium, the matrix released only about 28.56% of the entrapped flaxseed oil after 2 hours. The rest of the oil then released in the SIF medium, continuing for up to 5 h to release 99.32% of the oil. |
first_indexed | 2024-12-13T15:41:19Z |
format | Article |
id | doaj.art-ed48a1e4c7e84073b05a6f353ca09193 |
institution | Directory Open Access Journal |
issn | 2175-9790 |
language | English |
last_indexed | 2024-12-13T15:41:19Z |
publishDate | 2019-12-01 |
publisher | Universidade de São Paulo |
record_format | Article |
series | Brazilian Journal of Pharmaceutical Sciences |
spelling | doaj.art-ed48a1e4c7e84073b05a6f353ca091932022-12-21T23:39:50ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902019-12-015510.1590/s2175-97902019000200261Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelationZam Wissamhttps://orcid.org/0000-0002-2733-1884Housheh SamerThe objective of the current study was to encapsulate flaxseed oil extracted from finely grounded flaxseed powder and determined for its fatty acids content by GC/FID. Ionotropic gelation method was used to form beads containing 40% flaxseed oil with vitamin E being used as an antioxidant agent. The study employed calcium chloride solution as crosslinking agent with a combination of sodium alginate and salep. The effect of polymer concentrations and calcium chloride concentration on the morphology, entrapment efficiency and oil release was studied. The encapsulation efficiency reached 93.46 ± 0.064% using 0.6% of salep and 2% sodium alginate with 0.3M calcium chloride gelling solution. In SGF medium, the matrix released only about 28.56% of the entrapped flaxseed oil after 2 hours. The rest of the oil then released in the SIF medium, continuing for up to 5 h to release 99.32% of the oil.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100578&tlng=enFlaxseed oilSodium alginateSalepBeads |
spellingShingle | Zam Wissam Housheh Samer Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation Brazilian Journal of Pharmaceutical Sciences Flaxseed oil Sodium alginate Salep Beads |
title | Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation |
title_full | Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation |
title_fullStr | Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation |
title_full_unstemmed | Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation |
title_short | Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation |
title_sort | encapsulation of flaxseed oil extract in alginate salep system by ionic gelation |
topic | Flaxseed oil Sodium alginate Salep Beads |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100578&tlng=en |
work_keys_str_mv | AT zamwissam encapsulationofflaxseedoilextractinalginatesalepsystembyionicgelation AT houshehsamer encapsulationofflaxseedoilextractinalginatesalepsystembyionicgelation |