Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation

The objective of the current study was to encapsulate flaxseed oil extracted from finely grounded flaxseed powder and determined for its fatty acids content by GC/FID. Ionotropic gelation method was used to form beads containing 40% flaxseed oil with vitamin E being used as an antioxidant agent. The...

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Main Authors: Zam Wissam, Housheh Samer
Format: Article
Language:English
Published: Universidade de São Paulo 2019-12-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100578&tlng=en
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author Zam Wissam
Housheh Samer
author_facet Zam Wissam
Housheh Samer
author_sort Zam Wissam
collection DOAJ
description The objective of the current study was to encapsulate flaxseed oil extracted from finely grounded flaxseed powder and determined for its fatty acids content by GC/FID. Ionotropic gelation method was used to form beads containing 40% flaxseed oil with vitamin E being used as an antioxidant agent. The study employed calcium chloride solution as crosslinking agent with a combination of sodium alginate and salep. The effect of polymer concentrations and calcium chloride concentration on the morphology, entrapment efficiency and oil release was studied. The encapsulation efficiency reached 93.46 ± 0.064% using 0.6% of salep and 2% sodium alginate with 0.3M calcium chloride gelling solution. In SGF medium, the matrix released only about 28.56% of the entrapped flaxseed oil after 2 hours. The rest of the oil then released in the SIF medium, continuing for up to 5 h to release 99.32% of the oil.
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spelling doaj.art-ed48a1e4c7e84073b05a6f353ca091932022-12-21T23:39:50ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902019-12-015510.1590/s2175-97902019000200261Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelationZam Wissamhttps://orcid.org/0000-0002-2733-1884Housheh SamerThe objective of the current study was to encapsulate flaxseed oil extracted from finely grounded flaxseed powder and determined for its fatty acids content by GC/FID. Ionotropic gelation method was used to form beads containing 40% flaxseed oil with vitamin E being used as an antioxidant agent. The study employed calcium chloride solution as crosslinking agent with a combination of sodium alginate and salep. The effect of polymer concentrations and calcium chloride concentration on the morphology, entrapment efficiency and oil release was studied. The encapsulation efficiency reached 93.46 ± 0.064% using 0.6% of salep and 2% sodium alginate with 0.3M calcium chloride gelling solution. In SGF medium, the matrix released only about 28.56% of the entrapped flaxseed oil after 2 hours. The rest of the oil then released in the SIF medium, continuing for up to 5 h to release 99.32% of the oil.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100578&tlng=enFlaxseed oilSodium alginateSalepBeads
spellingShingle Zam Wissam
Housheh Samer
Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation
Brazilian Journal of Pharmaceutical Sciences
Flaxseed oil
Sodium alginate
Salep
Beads
title Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation
title_full Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation
title_fullStr Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation
title_full_unstemmed Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation
title_short Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation
title_sort encapsulation of flaxseed oil extract in alginate salep system by ionic gelation
topic Flaxseed oil
Sodium alginate
Salep
Beads
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100578&tlng=en
work_keys_str_mv AT zamwissam encapsulationofflaxseedoilextractinalginatesalepsystembyionicgelation
AT houshehsamer encapsulationofflaxseedoilextractinalginatesalepsystembyionicgelation