Host microRNAs are decreased in pediatric solid-organ transplant recipients during EBV+ Post-transplant Lymphoproliferative Disorder

Host microRNAs are decreased in pediatric solid-organ transplant recipients during EBV+ Post-transplant Lymphoproliferative Disorder

Post-transplant lymphoproliferative disorder (PTLD) is a serious complication of solid organ transplantation. Predisposing factors include primary Epstein-Barr virus (EBV) infection, reactivation of EBV in recipient B cells, and decreased T cell immunity due to immunosuppression. In our previous stu...

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Bibliographic Details
Main Authors: Ayantika Sen, Jeanna Enriquez, Mahil Rao, Marla Glass, Yarl Balachandran, Sharjeel Syed, Clare J. Twist, Kenneth Weinberg, Scott D. Boyd, Daniel Bernstein, Amber W. Trickey, Dita Gratzinger, Brent Tan, Mary Gay Lapasaran, Mark A. Robien, Merideth Brown, Brian Armstrong, Dev Desai, George Mazariegos, Clifford Chin, Thomas M. Fishbein, Robert S. Venick, Akin Tekin, Heiner Zimmermann, Ralf U. Trappe, Ioannis Anagnostopoulos, Carlos O. Esquivel, Olivia M. Martinez, Sheri M. Krams
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Post-Transplant Lymphoproliferative Disorder
microRNA
extracellular vesicles
Epstein-Barr Virus
solid-organ transplant
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.994552/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.994552/full

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