Passiflora tenuifila Killip: Assessment of chemical composition by 1H NMR and UPLC-ESI-Q-TOF-MSE and its bioactive properties in a rotenone-induced rat model of Parkinson’s disease
Passiflora tenuifila Killip is a wild species, with no studies regarding to functional properties. The objective of this work was to evaluate the chemical composition, including NMR and UPLC, toxicity and functional effect in a Parkinsonism model. The fruits (peel, pulp, and seed) were crushed, lyop...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-11-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464619304530 |
| _version_ | 1818598515183452160 |
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| author | Dayse Karine Rodrigues Holanda Nedio Jair Wurlitzer Ana Paula Dionísio Adriana Rolim Campos Edy Sousa de Brito Lorena Mara Alexandre e Silva Paulo Riceli Vasconcelos Ribeiro Ana Maria Costa Paulo Henrique Machado de Souza Francisco Arnaldo Viana Lima Renato de Azevedo Moreira |
| author_facet | Dayse Karine Rodrigues Holanda Nedio Jair Wurlitzer Ana Paula Dionísio Adriana Rolim Campos Edy Sousa de Brito Lorena Mara Alexandre e Silva Paulo Riceli Vasconcelos Ribeiro Ana Maria Costa Paulo Henrique Machado de Souza Francisco Arnaldo Viana Lima Renato de Azevedo Moreira |
| author_sort | Dayse Karine Rodrigues Holanda |
| collection | DOAJ |
| description | Passiflora tenuifila Killip is a wild species, with no studies regarding to functional properties. The objective of this work was to evaluate the chemical composition, including NMR and UPLC, toxicity and functional effect in a Parkinsonism model. The fruits (peel, pulp, and seed) were crushed, lyophilized and characterized. The subchronic toxicity was evaluated in Wistar rats during 90 days, and the Parkinsonism symptoms were induced by rotenone and after treated with P. tenuifila daily doses during 21 days. Composition results indicated a high total dietary fiber content, total polyphenols, and antioxidant activity. The subchronic toxicity results showed that garlic passion fruit did not present signs of toxicity. In the Parkinsonism model, the tests allow to indicate that the consumption of garlic passion fruit causes an improvement and possible effect of recovery of the damages induced by the rotenone, being these effects of improvement proportional to the consumption. |
| first_indexed | 2024-12-16T12:04:55Z |
| format | Article |
| id | doaj.art-ed4c21f9dede46fd992cab6aabad7774 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-16T12:04:55Z |
| publishDate | 2019-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-ed4c21f9dede46fd992cab6aabad77742022-12-21T22:32:20ZengElsevierJournal of Functional Foods1756-46462019-11-0162Passiflora tenuifila Killip: Assessment of chemical composition by 1H NMR and UPLC-ESI-Q-TOF-MSE and its bioactive properties in a rotenone-induced rat model of Parkinson’s diseaseDayse Karine Rodrigues Holanda0Nedio Jair Wurlitzer1Ana Paula Dionísio2Adriana Rolim Campos3Edy Sousa de Brito4Lorena Mara Alexandre e Silva5Paulo Riceli Vasconcelos Ribeiro6Ana Maria Costa7Paulo Henrique Machado de Souza8Francisco Arnaldo Viana Lima9Renato de Azevedo Moreira10Department of Food Engineering, Federal University of Ceará, Fortaleza, Ceará, BrazilEmbrapa Agroindústria Tropical, Dra Sara Mesquita, 2270, 60511-110 Fortaleza, Ceará, Brazil; Corresponding author.Embrapa Agroindústria Tropical, Dra Sara Mesquita, 2270, 60511-110 Fortaleza, Ceará, BrazilUNIFOR – University of Fortaleza, CE, BrazilEmbrapa Agroindústria Tropical, Dra Sara Mesquita, 2270, 60511-110 Fortaleza, Ceará, BrazilEmbrapa Agroindústria Tropical, Dra Sara Mesquita, 2270, 60511-110 Fortaleza, Ceará, BrazilEmbrapa Agroindústria Tropical, Dra Sara Mesquita, 2270, 60511-110 Fortaleza, Ceará, BrazilEmbrapa Cerrados, Brasília, DF, BrazilDepartment of Food Engineering, Federal University of Ceará, Fortaleza, Ceará, BrazilDepartment of Fisiology and Farmacology, Federal University of Ceará, Fortaleza, BrazilUNIFOR – University of Fortaleza, CE, BrazilPassiflora tenuifila Killip is a wild species, with no studies regarding to functional properties. The objective of this work was to evaluate the chemical composition, including NMR and UPLC, toxicity and functional effect in a Parkinsonism model. The fruits (peel, pulp, and seed) were crushed, lyophilized and characterized. The subchronic toxicity was evaluated in Wistar rats during 90 days, and the Parkinsonism symptoms were induced by rotenone and after treated with P. tenuifila daily doses during 21 days. Composition results indicated a high total dietary fiber content, total polyphenols, and antioxidant activity. The subchronic toxicity results showed that garlic passion fruit did not present signs of toxicity. In the Parkinsonism model, the tests allow to indicate that the consumption of garlic passion fruit causes an improvement and possible effect of recovery of the damages induced by the rotenone, being these effects of improvement proportional to the consumption.http://www.sciencedirect.com/science/article/pii/S1756464619304530Parkinsonism induced modelGarlic passion fruitAntioxidantPhenolic compounds |
| spellingShingle | Dayse Karine Rodrigues Holanda Nedio Jair Wurlitzer Ana Paula Dionísio Adriana Rolim Campos Edy Sousa de Brito Lorena Mara Alexandre e Silva Paulo Riceli Vasconcelos Ribeiro Ana Maria Costa Paulo Henrique Machado de Souza Francisco Arnaldo Viana Lima Renato de Azevedo Moreira Passiflora tenuifila Killip: Assessment of chemical composition by 1H NMR and UPLC-ESI-Q-TOF-MSE and its bioactive properties in a rotenone-induced rat model of Parkinson’s disease Journal of Functional Foods Parkinsonism induced model Garlic passion fruit Antioxidant Phenolic compounds |
| title | Passiflora tenuifila Killip: Assessment of chemical composition by 1H NMR and UPLC-ESI-Q-TOF-MSE and its bioactive properties in a rotenone-induced rat model of Parkinson’s disease |
| title_full | Passiflora tenuifila Killip: Assessment of chemical composition by 1H NMR and UPLC-ESI-Q-TOF-MSE and its bioactive properties in a rotenone-induced rat model of Parkinson’s disease |
| title_fullStr | Passiflora tenuifila Killip: Assessment of chemical composition by 1H NMR and UPLC-ESI-Q-TOF-MSE and its bioactive properties in a rotenone-induced rat model of Parkinson’s disease |
| title_full_unstemmed | Passiflora tenuifila Killip: Assessment of chemical composition by 1H NMR and UPLC-ESI-Q-TOF-MSE and its bioactive properties in a rotenone-induced rat model of Parkinson’s disease |
| title_short | Passiflora tenuifila Killip: Assessment of chemical composition by 1H NMR and UPLC-ESI-Q-TOF-MSE and its bioactive properties in a rotenone-induced rat model of Parkinson’s disease |
| title_sort | passiflora tenuifila killip assessment of chemical composition by 1h nmr and uplc esi q tof mse and its bioactive properties in a rotenone induced rat model of parkinson s disease |
| topic | Parkinsonism induced model Garlic passion fruit Antioxidant Phenolic compounds |
| url | http://www.sciencedirect.com/science/article/pii/S1756464619304530 |
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