Mechanisms of Cisplatin Nephrotoxicity

Mechanisms of Cisplatin Nephrotoxicity

Cisplatin is a widely used and highly effective cancer chemotherapeutic agent. One of the limiting side effects of cisplatin use is nephrotoxicity. Research over the past 10 years has uncovered many of the cellular mechanisms which underlie cisplatin-induced renal cell death. It has also become appa...

Full description

Bibliographic Details
Main Authors: Ganesan Ramesh, William Brian Reeves, Ronald P. Miller, Raghu K. Tadagavadi
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Toxins
Subjects:
cisplatin
inflammation
kidney injury
nephrotoxicity
apoptosis
dendritic cells
cytokines
toll-like receptors
Online Access:http://www.mdpi.com/2072-6651/2/11/2490/

Internet

http://www.mdpi.com/2072-6651/2/11/2490/

Similar Items