Exploration of the Binding Mechanism of Cyclic Dinucleotide Analogs to Stimulating Factor Proteins and the Implications for Subsequent Analog Drug Design

Exploration of the Binding Mechanism of Cyclic Dinucleotide Analogs to Stimulating Factor Proteins and the Implications for Subsequent Analog Drug Design

Cyclic dinucleotides (CDNs) are cyclic molecules consisting of two nucleoside monophosphates linked by two phosphodiester bonds, which act as a second messenger and bind to the interferon gene stimulating factor (STING) to activate the downstream signaling pathway and ultimately induce interferon se...

全面介绍

书目详细资料
Main Authors: Shu-Wei Yuan, Hong-Ling Shi, Mu-Ran Fu, Xi-Chuan Zhang, Xiao-Qi Xi, Yao Wang, Tai-Song Shen, Jin-Liang Ma, Cun-Duo Tang
格式: 文件
语言:English
出版: MDPI AG 2024-03-01
丛编:Biomolecules
主题:
cyclic dinucleotides
analogs
stimulator of interferon genes
adjuvants
second messenger
computer simulations
在线阅读:https://www.mdpi.com/2218-273X/14/3/350

因特网

https://www.mdpi.com/2218-273X/14/3/350

相似书籍