Structure of an MHC I–tapasin–ERp57 editing complex defines chaperone promiscuity

Adaptive immunity depends on cellular chaperone and quality control systems that are decisive for an effective presentation of foreign antigens via MHC I molecules. Here, the authors present the structure of a key chaperone-MHC I complex.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ines Katharina Müller, Christian Winter, Christoph Thomas, Robbert M. Spaapen, Simon Trowitzsch, Robert Tampé
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Nature Portfolio 2022-09-01
Σειρά:Nature Communications
Διαθέσιμο Online:https://doi.org/10.1038/s41467-022-32841-9