History of the discovery, development, and FDA-approval of buprenorphine medications for the treatment of opioid use disorder

Buprenorphine-based medications were first approved by the United States Food and Drug Administration in 2002 for the treatment of opioid dependence, or opioid use disorder (OUD) as the condition is presently known. This regulatory milestone was the outcome of 36 years of research and development, w...

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Bibliographic Details
Main Authors: Christian Heidbreder, Paul J. Fudala, Mark K. Greenwald
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Drug and Alcohol Dependence Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772724623000033