The IL-17-IL-17RA axis is required to promote osteosarcoma progression in mice

The IL-17-IL-17RA axis is required to promote osteosarcoma progression in mice

Abstract Osteosarcoma is rare but is the most common bone tumor. Diagnostic tools such as magnetic resonance imaging development of chemotherapeutic agents have increased the survival rate in osteosarcoma patients, although 5-year survival has plateaued at 70%. Thus, development of new treatment app...

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Main Authors: Naoto Yoshimura, Ryusho Kariya, Masaki Shimada, Makoto Tateyama, Hideto Matsunaga, Yuto Shibata, Shuntaro Tanimura, Kosei Takata, Takahiro Arima, Junki Kawakami, Kazuya Maeda, Yuko Fukuma, Masaru Uragami, Katsumasa Ideo, Kazuki Sugimoto, Ryuji Yonemitsu, Kozo Matsushita, Satoshi Hisanaga, Masaki Yugami, Yusuke Uehara, Tetsuro Masuda, Takayuki Nakamura, Takuya Tokunaga, Tatsuki Karasugi, Takanao Sueyoshi, Hiro Sato, Yoichiro Iwakura, Kimi Araki, Eisuke Kobayashi, Seiji Okada, Takeshi Miyamoto
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-49016-1

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https://doi.org/10.1038/s41598-023-49016-1

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