An Immunoregulatory Role for Complement Receptors in Murine Models of Breast Cancer

An Immunoregulatory Role for Complement Receptors in Murine Models of Breast Cancer

The complement system has demonstrated roles in regulating tumor growth, although these may differ between tumor types. The current study used two murine breast cancer models (EMT6 and 4T1) to investigate whether pharmacological targeting of receptors for complement proteins C3a (C3aR) and C5a (C5aR...

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Bibliographic Details
Main Authors: Fazrena Nadia Md Akhir, Mohd Hezmee Mohd Noor, Keith Weng Kit Leong, Jamileh A. Nabizadeh, Helga D. Manthey, Stefan E. Sonderegger, Jenny Nga Ting Fung, Crystal E. McGirr, Ian A. Shiels, Paul C. Mills, Trent M. Woodruff, Barbara E. Rolfe
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Antibodies
Subjects:
complement C5a
complement C3a
complement receptors
mammary carcinoma
immunoregulation
tumor infiltrating leukocytes
Online Access:https://www.mdpi.com/2073-4468/10/1/2

Internet

https://www.mdpi.com/2073-4468/10/1/2

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