cMyc increases cell number through uncoupling of cell division from cell size in CHO cells

<p>Abstract</p> <p>Background</p> <p>Over the past decades, the increase in maximal cell numbers for the production of mammalian derived biologics has been in a large part due to the development of optimal feeding strategies. Engineering of the cell line is one of proba...

Full description

Bibliographic Details
Main Authors: Kuystermans Darrin, Al-Rubeai Mohamed
Format: Article
Language:English
Published: BMC 2009-09-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/9/76