DNA-Directed Protein Anchoring on Oligo/Alkanethiol-Coated Gold Nanoparticles: A Versatile Platform for Biosensing Applications

DNA-Directed Protein Anchoring on Oligo/Alkanethiol-Coated Gold Nanoparticles: A Versatile Platform for Biosensing Applications

Herein, we report on a smart biosensing platform that exploits gold nanoparticles (AuNPs) functionalized through ssDNA self-assembled monolayers (SAM) and the DNA-directed immobilization (DDI) of DNA-protein conjugates; a novel, high-sensitivity optical characterization technique based on a miniatur...

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Bibliographic Details
Main Authors: Ahmed Alsadig, Behnaz Abbasgholi-NA, Hendrik Vondracek, Barbara Medagli, Sara Fortuna, Paola Posocco, Pietro Parisse, Humberto Cabrera, Loredana Casalis
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Nanomaterials
Subjects:
DNA-directed immobilization (DDI)
gold nanoparticles (AuNPs)
plasmonic immunoassays
thermal lens spectroscopy (TLS)
biosensing
circulating disease biomarkers
Online Access:https://www.mdpi.com/2079-4991/13/1/78

Internet

https://www.mdpi.com/2079-4991/13/1/78

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