Self-assembled chitosan-sodium usnate drug delivery nanosystems: Synthesis, characterization, stability studies, in vitro cytotoxicity and in vivo biocompatibility against 143 B cells

Self-assembled chitosan-sodium usnate drug delivery nanosystems: Synthesis, characterization, stability studies, in vitro cytotoxicity and in vivo biocompatibility against 143 B cells

Polymers are among the most studied materials as drug carriers, due to their tunable chemical structure and ability to self-assemble to give different types of nanostructures. In this study, chitosan (CS) nanoparticles (NPs) were investigated as carriers for the anticancer drug sodium usnate (NaU) f...

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Bibliographic Details
Main Authors: Benedetta Brugnoli, Alessia Mariano, Beatrice Simonis, Cecilia Bombelli, Simona Sennato, Antonella Piozzi, Vincenzo Taresco, Veeren M. Chauhan, Steven M. Howdle, Anna Scotto d'Abusco, Iolanda Francolini
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Carbohydrate Polymer Technologies and Applications
Subjects:
Chitosan nanoparticles
Nano-particle drug delivery systems
Caenorhabditis elegans nematodes
Sodium usnate
143B cells Maspin stimulation
Osteosarcoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2666893923000944

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http://www.sciencedirect.com/science/article/pii/S2666893923000944

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