Discovery of Galangin as a Potential DPP-4 Inhibitor That Improves Insulin-Stimulated Skeletal Muscle Glucose Uptake: A Combinational Therapy for Diabetes

Discovery of Galangin as a Potential DPP-4 Inhibitor That Improves Insulin-Stimulated Skeletal Muscle Glucose Uptake: A Combinational Therapy for Diabetes

Dipeptidyl peptidase-4 (DPP-4) is a well-known therapeutic drug target proven to reduce blood glucose levels in diabetes mellitus, and clinically, DPP-4 inhibitors are used in combination with other anti-diabetic agents. However, side effects and skeletal muscle health are not considered in the trea...

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Bibliographic Details
Main Authors: Poonam Kalhotra, Veera C. S. R. Chittepu, Guillermo Osorio-Revilla, Tzayhri Gallardo-Velázquez
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
diabetes mellitus
molecular docking
galangin
DPP-4 inhibitor
combination therapy
skeletal muscle cell health
Online Access:http://www.mdpi.com/1422-0067/20/5/1228

Internet

http://www.mdpi.com/1422-0067/20/5/1228

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