Tectorigenin Alleviates Inflammation, Apoptosis, and Ossification in Rat Tendon-Derived Stem Cells via Modulating NF-Kappa B and MAPK Pathways

Tectorigenin Alleviates Inflammation, Apoptosis, and Ossification in Rat Tendon-Derived Stem Cells via Modulating NF-Kappa B and MAPK Pathways

Tendinopathy is a common musculoskeletal disorder that mainly affects athletes and people of older age. Tumor necrosis factor-α (TNF-α) plays an important role in initiating tendinopathy. Tectorigenin, an extract component of Belam-canda Chinesis, possesses anti-inflammatory and anti-apoptosis activ...

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Bibliographic Details
Main Authors: Safwat Adel Abdo Moqbel, Kai Xu, Zhonggai Chen, Langhai Xu, Yuezhe He, Zhipeng Wu, Chiyuan Ma, Jisheng Ran, Lidong Wu, Yan Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TDSCs
tectorigenin
TNF-α
inflammation
apoptosis
ossification
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.568894/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.568894/full

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