Multi-omics investigation of Clostridioides difficile-colonized patients reveals pathogen and commensal correlates of C. difficile pathogenesis

Multi-omics investigation of Clostridioides difficile-colonized patients reveals pathogen and commensal correlates of C. difficile pathogenesis

Clostridioides difficile infection (CDI) imposes a substantial burden on the health care system in the United States. Understanding the biological basis for the spectrum of C. difficile-related disease manifestations is imperative to improving treatment and prevention of CDI. Here, we investigate th...

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Bibliographic Details
Main Authors: Skye RS Fishbein, John I Robinson, Tiffany Hink, Kimberly A Reske, Erin P Newcomer, Carey-Ann D Burnham, Jeffrey P Henderson, Erik R Dubberke, Gautam Dantas
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-01-01
Series:eLife
Subjects:
Clostridioides difficile
gut microbiome
colonization resistance
Online Access:https://elifesciences.org/articles/72801

Internet

https://elifesciences.org/articles/72801

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