Unique characteristics of the tumor immune microenvironment in young patients with metastatic colorectal cancer

Unique characteristics of the tumor immune microenvironment in young patients with metastatic colorectal cancer

IntroductionMetastatic colorectal cancer (mCRC) remains a common and highly morbid disease, with a recent increase in incidence in patients younger than 50 years. There is an acute need to better understand differences in tumor biology, molecular characteristics, and other age-related differences in...

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Bibliographic Details
Main Authors: Brian D. Griffith, Jenny Lazarus, Jake McGue, Santhoshi Krishnan, Michael I. D’Angelica, Jinru Shia, Irina Dobrosotskaya, Jaiqi Shi, Jacob Edwards, Arvind Rao, Timothy L. Frankel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
tumor immunology
colorectal cancer
immunotherapy
spatial relation analysis
multiplex immunohistochemistry (IHC)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1289402/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1289402/full

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