Anti-angiogenic effects of differentiation-inducing factor-1 involving VEGFR-2 expression inhibition independent of the Wnt/β-catenin signaling pathway

<p>Abstract</p> <p>Background</p> <p>Differentiation-inducing factor-1 (DIF-1) is a putative morphogen that induces cell differentiation in <it>Dictyostelium discoideum</it>. DIF-1 inhibits proliferation of various mammalian tumor cells by suppressing the ca...

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Bibliographic Details
Main Authors: Yoshihara Tatsuya, Takahashi-Yanaga Fumi, Shiraishi Fumie, Morimoto Sachio, Watanabe Yutaka, Hirata Masato, Hoka Sumio, Sasaguri Toshiyuki
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/245