Accurate GM atrophy quantification in MS using lesion-filling with co-registered 2D lesion masks

Background: In multiple sclerosis (MS), brain atrophy quantification is affected by white matter lesions. LEAP and FSL-lesion_filling, replace lesion voxels with white matter intensities; however, they require precise lesion identification on 3DT1-images. Aim: To determine whether 2DT2 lesion masks...

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Bibliographic Details
Main Authors: V. Popescu, N.C.G. Ran, F. Barkhof, D.T. Chard, C.A. Wheeler-Kingshott, H. Vrenken
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:NeuroImage: Clinical
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158214000059