The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance

The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance

Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major negative regulator for insulin receptor signaling and a novel molecular player in e...

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Bibliographic Details
Main Authors: Shahenda S. Abdelsalam, Hesham M. Korashy, Asad Zeidan, Abdelali Agouni
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Biomolecules
Subjects:
PTP1B
cardiovascular disease
endothelial dysfunction
insulin resistance
diabetes
Online Access:https://www.mdpi.com/2218-273X/9/7/286

Internet

https://www.mdpi.com/2218-273X/9/7/286

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