Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction

Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction

Abstract Brain levels of the endocannabinoid 2-arachidonoylglycerol (2-AG) shape motivated behavior and nucleus accumbens (NAc) dopamine release. However, it is not clear whether mobilization of 2-AG specifically from midbrain dopamine neurons is necessary for dopaminergic responses to external stim...

Full description

Bibliographic Details
Main Authors: Miguel Á. Luján, Dan P. Covey, Reana Young-Morrison, LanYuan Zhang, Andrew Kim, Fiorella Morgado, Sachin Patel, Caroline E. Bass, Carlos Paladini, Joseph F. Cheer
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43131-3

Internet

https://doi.org/10.1038/s41467-023-43131-3

Similar Items