Nicorandil Elevates Tissue cGMP Levels in a Nitric-Oxide-Independent Manner
The K+ channel opener nicorandil is a hybrid compound that contains nitrate in its structure. It has been reported that nicorandil can relax vascular tissue in vitro via a mechanism that involves activation of KATP channels and stimulation of soluble guanylyl cyclase. However, it is not known whethe...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319343361 |