In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice

In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice

The aim of this study is to evaluate the anticonvulsant potential of schisandrin B, a main ingredient of <i>Schisandra chinensis</i> extracts. Schisandrin B showed anticonvulsant activity in the zebrafish larva pentylenetetrazole acute seizure assay but did not alter seizure thresholds i...

Full description

Bibliographic Details
Main Authors: Dorota Nieoczym, Nancy Saana Banono, Katarzyna Stępnik, Agnieszka A. Kaczor, Przemysław Szybkowski, Camila Vicencio Esguerra, Wirginia Kukula-Koch, Kinga Gawel
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
schisandrin B
seizures
toxicity
zebrafish
mice
pentylenetetrazole
Online Access:https://www.mdpi.com/1422-0067/24/16/12949

Internet

https://www.mdpi.com/1422-0067/24/16/12949

Similar Items