Preparation of PLGA microspheres loaded with niclosamide via microfluidic technology and their inhibition of Caco-2 cell activity in vitro

Niclosamide (NIC) is a multifunctional drug that regulates various signaling pathways and biological processes. It is widely used for the treatment of cancer, viral infections, and metabolic disorders. However, its low water solubility limits its efficacy. In this study, poly(lactic-co-glycolic acid...

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Bibliographic Details
Main Authors: Yulei Tai, Menglun Tian, Yu Chen, Peijun You, Xiaojun Song, Bangting Xu, Cidong Duan, Dazhi Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1249293/full