Comprehensive analysis of SLC43A2 on the tumor immune microenvironment and prognosis of liver hepatocellular carcinoma

Comprehensive analysis of SLC43A2 on the tumor immune microenvironment and prognosis of liver hepatocellular carcinoma

Background: Tumor cells outcompete T cells for methionine via overexpressing SLC43A2, causing T cells exhaustion. We explored the influence of SLC43A2 on tumor immune microenvironment (TIME), immune-related genes (IRGs) and the prognosis of liver hepatocellular carcinoma (LIHC) patients.Methods: The...

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Bibliographic Details
Main Authors: Yan Liao, Junmei Weng, Lian Chen, Nan Hu, Xun Yuan, Jianhua Wang, Feng He, Yixin Cai, Qin Huang, Jianing Wang, Liu Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
liver hepatocellular carcinoma (LIHC)
SLC43A2
tumor immune microenvironment (TIME)
prognostic risk score model
prognostic biomarker
therapeutic target
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.911378/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.911378/full

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