Tumor-derived exosomes, myeloid-derived suppressor cells, and tumor microenvironment

Abstract Plenty of immune cells infiltrate into the tumor microenvironment (TME) during tumor progression, in which myeloid-derived suppressor cells (MDSCs) represent a heterogeneous population of immature myeloid cells with immunosuppressive activity. Tumor cells and stromal cells facilitate the ac...

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Bibliographic Details
Main Authors: Xinyu Tian, Han Shen, Zhiyang Li, Tingting Wang, Shengjun Wang
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13045-019-0772-z