Characteristics of the Gut Microbiome and IL-13/TGF-β1 Mediated Fibrosis in Post-Kasai Cholangitis of Biliary Atresia

Characteristics of the Gut Microbiome and IL-13/TGF-β1 Mediated Fibrosis in Post-Kasai Cholangitis of Biliary Atresia

Aims: Cholangitis in biliary atresia (BA), which accelerates liver fibrosis progression, is among the most common serious complications after Kasai surgery; however, its etiology remains elusive. Gut microbiome migration may contribute to post-Kasai cholangitis. Further, there is no appropriate mode...

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Bibliographic Details
Main Authors: Lingdu Meng, Jia Liu, Junfeng Wang, Min Du, Shouhua Zhang, Yanlei Huang, Zhen Shen, Rui Dong, Gong Chen, Shan Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pediatrics
Subjects:
biliary atresia
cholangitis
gut microbiome
Kasai procedure
Klebsiella pneumoniae
organoid
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.751204/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2021.751204/full

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