Lower baseline testosterone level is related to earlier development of castration resistance in metastatic prostate cancer: a multi-center cohort study

Lower baseline testosterone level is related to earlier development of castration resistance in metastatic prostate cancer: a multi-center cohort study

PurposeIn the era of concurrent combination therapy in metastatic hormone sensitive prostate cancer, the impact of the testosterone level before initiating androgen deprivation therapy on treatment outcome is still uncertain. We aimed to investigate its effect on time-to-castration-resistance in a m...

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Bibliographic Details
Main Authors: Ho Ming Chris Wong, Peter Ka-Fung Chiu, Ignacio Puche-Sanz, Zhao Xue, Dong-Ning Chen, Enrique Gomez-Gomez, Isabel Heidegger, Mona Kafka, Yong Wei, Shinichi Sakamoto, Anthony Chi Fai Ng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
MHSPC
testosterone
combination (combined) therapy
mCRPC
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1321522/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1321522/full

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