Targeting NLRP3-Mediated Neuroinflammation in Alzheimer’s Disease Treatment

Targeting NLRP3-Mediated Neuroinflammation in Alzheimer’s Disease Treatment

Alzheimer’s disease (AD) is the most common cause of dementia in the general population and, to date, constitutes a major therapeutic challenge. In the pathogenesis of AD, aggregates of amyloid β (Aβ) and neurofibrillary tangles (NFTs) containing Tau-microtubule-associated protein (tau) are known to...

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Bibliographic Details
Main Authors: Julia Barczuk, Natalia Siwecka, Weronika Lusa, Wioletta Rozpędek-Kamińska, Ewa Kucharska, Ireneusz Majsterek
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
amyloid β
neurofibrillary tangles
NOD-like receptor pyrin domain-containing 3
NOD-like receptor pyrin domain-containing 3 inflammasome
NOD-like receptor pyrin domain-containing 3 inhibitors
Online Access:https://www.mdpi.com/1422-0067/23/16/8979

Internet

https://www.mdpi.com/1422-0067/23/16/8979

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