IL-7 signalling represses Bcl-6 and the TFH gene program
It remains incompletely understood how cytokines shape TH1 cell differentiation to central memory T (TCM) and follicular T helper (TFH) cells. Here the authors show that TH1 cells can co-initiate the expression of both TFH and TCM gene programs and that IL-7 signalling represses TFH-associated but n...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2016-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms10285 |