miR-144 delivered by nasopharyngeal carcinoma-derived EVs stimulates angiogenesis through the FBXW7/HIF-1α/VEGF-A axis

miR-144 delivered by nasopharyngeal carcinoma-derived EVs stimulates angiogenesis through the FBXW7/HIF-1α/VEGF-A axis

The current study aimed to explore the role of tumor-derived extracellular vesicles (EVs) in angiogenesis during nasopharyngeal carcinoma (NPC). NPC biopsy specimens were initially collected. Human umbilical vein endothelial cells (HUVECs) were co-cultured with EVs isolated from NPC cells, after whi...

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Bibliographic Details
Main Authors: Xiaoyan Tian, Yuehui Liu, Zhi Wang, Shuhong Wu
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
nasopharyngeal carcinoma
extracellular vesicle
microRNA-144
FBXW7
HIF-1α
vascular endothelial growth factor
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121000871

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http://www.sciencedirect.com/science/article/pii/S2162253121000871

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