Novel Biomarkers of Health and Degeneration in Human Intervertebral Discs: In-depth Proteomic Analysis of Collagen Framework of Fetal, Healthy, Scoliotic, Degenerate, and Herniated Discs

Study Design Profiling proteins expressed in the nucleus pulposus (NP) of intervertebral discs (IVDs) in five different biological states. Purpose To evaluate the molecular complexity of the collagen (COL) framework and its role in the health and disease of human IVDs. Overview of Literature Changes...

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Main Authors: Shanmuganathan Rajasekaran, Dilip Chand Raja Soundararajan, Sharon Miracle Nayagam, Chitraa Tangavel, Muthuraja Raveendran, KS Sri Vijay Anand, Ajoy Prasad Shetty, Rishi Mugesh Kanna
Format: Article
Language:English
Published: Korean Spine Society 2023-02-01
Series:Asian Spine Journal
Subjects:
Online Access:http://www.asianspinejournal.org/upload/pdf/asj-2021-0535.pdf