Multi-spectroscopic investigation of the binding interaction of fosfomycin with bovine serum albumin

The interaction between fosfomycin (FOS) and bovine serum albumin (BSA) has been investigated effectively by multi-spectroscopic techniques under physiological pH 7.4. FOS quenched the intrinsic fluorescence of BSA via static quenching. The number of binding sites n and observed binding constant KA...

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Bibliographic Details
Main Authors: Manjunath D. Meti, Sharanappa T. Nandibewoor, Shrinivas D. Joshi, Uttam A. More, Shivamurti A. Chimatadar
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177915000167