Schisantherin A Attenuates Neuroinflammation in Activated Microglia: Role of Nrf2 Activation Through ERK Phosphorylation

Schisantherin A Attenuates Neuroinflammation in Activated Microglia: Role of Nrf2 Activation Through ERK Phosphorylation

Background/Aims: In the present study, we investigated whether schisantherin A (StA) had anti-inflammatory effects under neuroinflammatory conditions. Methods: The effects of StA and its underlying mechanisms were examined in lipopolysaccharide (LPS)-activated BV-2 microglial cells by ELISA, qPCR, E...

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Bibliographic Details
Main Authors: Chuwen Li, Tongkai Chen, Hefeng Zhou, Chao Zhang, Yu Feng, Fan Tang, Maggie Pui-Man Hoi, Chengwei He, Ying Zheng, Simon Ming-Yuen Lee
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Schisantherin A
Neuroinflammation
Microglia
Nrf2
NF-κB
Online Access:https://www.karger.com/Article/FullText/491059

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https://www.karger.com/Article/FullText/491059

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