Concept and application of the probability of pharmacological success (PoPS) as a decision tool in drug development: a position paper
Abstract Background In drug development, few molecules from a large pool of early candidates become successful medicines after demonstrating a favourable benefit-risk ratio. Many decisions are made along the way to continue or stop the development of a molecule. The probability of pharmacological su...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-01-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-022-03849-y |