Concept and application of the probability of pharmacological success (PoPS) as a decision tool in drug development: a position paper

Abstract Background In drug development, few molecules from a large pool of early candidates become successful medicines after demonstrating a favourable benefit-risk ratio. Many decisions are made along the way to continue or stop the development of a molecule. The probability of pharmacological su...

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Bibliographic Details
Main Authors: Chao Chen, Xuan Zhou, Silvia Maria Lavezzi, Usman Arshad, Raman Sharma
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-022-03849-y