Ingested Ketone Ester Leads to a Rapid Rise of Acetyl-CoA and Competes with Glucose Metabolism in the Brain of Non-Fasted Mice

Ingested Ketone Ester Leads to a Rapid Rise of Acetyl-CoA and Competes with Glucose Metabolism in the Brain of Non-Fasted Mice

The role of ketone bodies in the cerebral energy homeostasis of neurological diseases has begun to attract recent attention particularly in acute neurological diseases. In ketogenic therapies, ketosis is achieved by either a ketogenic diet or by the administration of exogenous ketone bodies. The ora...

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Bibliographic Details
Main Authors: Laurent Suissa, Pavel Kotchetkov, Jean-Marie Guigonis, Emilie Doche, Ophélie Osman, Thierry Pourcher, Sabine Lindenthal
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
ketosis
ketogenic diet
exogenous ketone bodies
ketone ester
β-hydroxybutyrate
cerebral energy metabolism
Online Access:https://www.mdpi.com/1422-0067/22/2/524

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https://www.mdpi.com/1422-0067/22/2/524

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