Exome-wide association study reveals largely distinct gene sets underlying specific resistance to dengue virus types 1 and 3 in Aedes aegypti.

Exome-wide association study reveals largely distinct gene sets underlying specific resistance to dengue virus types 1 and 3 in Aedes aegypti.

Although specific interactions between host and pathogen genotypes have been well documented in invertebrates, the identification of host genes involved in discriminating pathogen genotypes remains a challenge. In the mosquito Aedes aegypti, the main dengue virus (DENV) vector worldwide, statistical...

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Bibliographic Details
Main Authors: Laura B Dickson, Sarah H Merkling, Mathieu Gautier, Amine Ghozlane, Davy Jiolle, Christophe Paupy, Diego Ayala, Isabelle Moltini-Conclois, Albin Fontaine, Louis Lambrechts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-05-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008794

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https://doi.org/10.1371/journal.pgen.1008794

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