UV-induced senescence of human dermal fibroblasts restrained by low-stiffness matrix by inhibiting NF-κB activation

As a hallmark of skin aging, senescent human dermal fibroblasts (HDFs) are known to lose the ability to divide. However, they can still interact with their cellular environment and the surrounding matrix. As the skin ages, the progressive slowing down of HDFs function decreases the skin's struc...

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Bibliographic Details
Main Authors: Xuefeng Yao, Huaqiong Li, Liping Chen, Lay Poh Tan
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-12-01
Series:Engineered Regeneration
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666138122000536