Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training

Abstract Regular exercise elicits advantageous metabolic adaptations in skeletal muscle, such as improved insulin sensitivity. However, the underpinning molecular mechanisms and the effect of diet on muscle exercise training benefits are unclear. We therefore characterized the skeletal muscle proteo...

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Bibliographic Details
Main Authors: Maximilian Kleinert, Benjamin L. Parker, Thomas E. Jensen, Steffen H. Raun, Phung Pham, Xiuqing Han, David E. James, Erik A. Richter, Lykke Sylow
Format: Article
Language:English
Published: Nature Portfolio 2018-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-28540-5