Engineering chromosome rearrangements in cancer

The identification of large chromosomal rearrangements in cancers has multiplied exponentially over the last decade. These complex and often rare genomic events have traditionally been challenging to study, in part owing to lack of tools that efficiently engineer disease-associated inversions, delet...

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Bibliographic Details
Main Authors: Salvador Alonso, Lukas E. Dow
Format: Article
Language:English
Published: The Company of Biologists 2021-09-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/14/9/dmm049078