Proteomic profiling of human keratinocytes undergoing UVB-induced alternative differentiation reveals TRIpartite Motif Protein 29 as a survival factor.

BACKGROUND: Repeated exposures to UVB of human keratinocytes lacking functional p16(INK-4a) and able to differentiate induce an alternative state of differentiation rather than stress-induced premature senescence. METHODOLOGY/PRINCIPAL FINDINGS: A 2D-DIGE proteomic profiling of this alternative stat...

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Main Authors: Véronique Bertrand-Vallery, Nathalie Belot, Marc Dieu, Edouard Delaive, Noëlle Ninane, Catherine Demazy, Martine Raes, Michel Salmon, Yves Poumay, Florence Debacq-Chainiaux, Olivier Toussaint
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2862717?pdf=render